It is recommended that you back up your files before running the Windows repair, to avoid losing any files. To resolve this issue, usually a Windows repair is needed to replace the corrupted system files. Mouse wheel issues can also be due to corrupt system files in Windows. Why is my Microsoft mouse wheel not working? There are tabs in this stock Dell one, that force you to pull back rather than immediately out. Pull up on the back of the mouse, and pull back. This will probably take a jewelers screwdriver, since they are pretty small screws. Locate the screws on the bottom of your mouse and unscrew them. Frequently Asked Questions How do you fix a mouse wheel?